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More and more studies have found that oxidative stress injury is involved in the pathological process of cognitive dysfunction in schizophrenia patients (16, 40)

A., Fenton, S

A , Representative images of GluA1 (yellow), PSD95 (green), synaptophysin (red) and MAP2 (cyan) immunostaining of primary hippocampal neuron cultures subjected to cLTP or not (vehicle) in a 3D rendering via Leica LAS X

[DOI] [PubMed] [Google Scholar] 708.Koppenol WH

Overexpression of NOX4 inhibits mitochondrial respiration by reducing mitochondrial protein complexes, promoting mitochondrial ROS production, and thus inducing ferroptosis in astrocytes