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doi: 10.1038/s41586-020-2222-z 108 NajmAMassonFMPreussPGeorgesSOryBQuillardTet al

Theabrownin has been shown to reverse insulin resistance in HepG2 cells through the IRS/PI3K/Akt signaling pathway, to regulate GSK3, G6Pase, glucokinase, PEPCK1 and other related indicators, reduce oxidative stress (83)

Given the pivotal role of mitochondria in energy production, their damage can significantly reduce sperm motility and vitality, diminishing reproductive potential [27]

[DOI] [PubMed] [Google Scholar] 26.Bloomfield SF, Rook GA, Scott EA, Shanahan F, Stanwell-Smith R, Turner P