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96 The major endogenous nonenzymatic low-molecular-mass antioxidants include N-acetylcysteine, glutathione, uric acid, melatonin, coenzyme Q and others

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90 Knockdown of isocitrate dehydrogenase 2 reduces the level of nicotinamide adenine dinucleotide phosphate, which is a key factor in maintaining the GSH-dependent mitochondrial antioxidant defense system, thereby promoting erastin-induced ferroptosis in HCC cells