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Actions of anti-GluR delta Ab were examined using monoclonal Ab against H2 ligand binding site of GluR delta, and not using Abs obtained from ataxic patients [58]

Coinhibition of GPX and Nrf2 also has a synergistic effect on ovarian cancer, which is particularly susceptible to ferroptosis due to its iron addiction. A study showed that combining Nrf2 inhibitors (e.g., ML385) with GPX4 inhibitors synergistically suppressed ovarian cancer by inducing ROS accumulation, lipid peroxidation, and caspase-3 activation, promoting ferroptosis and apoptosis

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