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10.1016/j.cell.2019.02.029 90 JusteauG.Gerves-PinquieC.Le VaillantM.TrzepizurW.MeslierN.GoupilF.et al (2020)

One patient felt some abdominal pain at the introduction of treatment, then we increased progressively the treatment to reach the maximum dose after 3 weeks without recurrence of the abdominal pain