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The condition is named after the Spanish dermatologist, Juan Nicolau, who reported the first case in 1924 using bismuth salts to treat syphilis.[] Despite being a relatively rare condition, NS can erratically result in severe morbidity and mortality, making it necessary for healthcare professionals to be vigilant in recognizing and managing this condition

In DOX-treated cells and mouse hearts, levels of NLRP3 and related proteins were elevated, and calycosin (CA) ameliorated cardiotoxicity via the NLRP3 pathway (99)

Combined with advances in single-cell biology, nanomedicine, and gene therapy, these approaches promise a new generation of precision redox therapeutics

Sato H, Shiiya A, Kimata M, Maebara K, Tamba M, Sakakura Y, Makino N, Sugiyama F, Yagami K, Moriguchi T, et al

You create receptor competition and introduce unnecessary side effects