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It is generally well-tolerated, with the following side effects [9][18]: GI symptoms (most common): Nausea, vomiting, diarrhea, and abdominal discomfort, particularly at doses above 1,200 mg/day Sulfurous taste/smell: NAC has a distinct sulfur odor and taste that some find unpleasant Headache: Occasionally reported Anaphylactoid reactions (IV use only): Infusion-related reactions including flushing, itching, bronchospasm, and hypotension occur in approximately 10-20% of patients receiving IV NAC for acetaminophen overdose [18] Upper limit: There is no established UL for NAC

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[DOI] [PubMed] [Google Scholar] 124.Khanam J., Hossain D., Hosen B., Uddin M., Kabir A., Anwarul Bari M

Protection: The liposome acts as a shield against stomach acid

Injection-site bruising is probably the most common complaint we hear - that little purple mark where the needle went in