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TargetP2.0 (T) [46], LOCALIZER (L) [47] and PredAlgo (P) [48] predictions (Additional file 1 Table S1) indicate highly variable targeting of the multiple DHAR paralogs (M, mitochondria

This distinction is crucial not only for ethical practice but for legal protection in academic and commercial research environments

Permissions Signed consent for the publishing of photographs was acquired for the use of all anonymous patient images in Figure 2

21 The regional ethics committee, Jordbruksverket, approved the experimental protocol and the method was carried out in accordance with the approved guidelines

The criteria for establishing and selecting appropriate animal models for hepatotoxicity assessment vary depending on the purpose of the study, the specific type of liver damage being evaluated, and the characteristics of the drug