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A dedicated study reported that expression of the antioxidant receptors and enzymes was significantly reduced in mice with diabetes, whereas markers for oxidative stress were significantly increased [190]

[21] SODs catalyze the production of O 2 and H 2 O 2 from superoxide (O 2 ), which results in less harmful reactants

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The DNA methylation profile (methylome) is inherited (maintenance DNA methylation), while the formation of new sites is de novo DNA methylation
