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doi: 10.1056/NEJMoa0908056

Curcumin in vitro neuroprotective effects are mediated by p62/keap-1/Nrf2 and PI3K/AKT Signaling pathway and autophagy inhibition

PLoS One , 10 ( 7 ), e0134506

The SURMOUNT-1 trial demonstrated 20.9% mean body weight reduction with tirzepatide 15mg weekly at 72 weeks, while preclinical 5-amino-1MQ studies showed visceral fat reduction independent of caloric restriction

Unfortunately, its also one of the most common vitamin deficiencies worldwide, particularly during the winter months
