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Extracts in Mice. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives 18, no

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Current clinical strategies for the management of PDN include glycolic control and treatment with drugs such as tricyclic compounds, serotonin noradrenalin reuptake inhibitors, -lipoic acid, anticonvulsants, opiates, membrane stabilizers and topical capsaicin

Stimulating pyruvate dehydrogenase complex reduces itaconate levels and enhances TCA cycle anabolic bioenergetics in acutely inflamed monocytes

The formation of NETs relies on neutrophil oxidative stress and the synergistic regulation of multiple molecular signaling pathways, making drug interventions targeting the NETosis process a potential therapeutic target for alleviating HIRI