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These symptoms occur most frequently during treatment initiation and dose escalation, with median durations of 2-8 days per episode

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During acute inflammation, TNF- is produced by macrophages which leads to a cascade of events that results in cell death via necrosis and apoptosis

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[DOI] [PMC free article] [PubMed] [Google Scholar] 298.Zhou HY, Zhu H, Yao XM, Qian JP, Yang J, Pan XD, Chen XD
