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Genome-wide association of hypoxia-inducible factor (HIF)-1 and HIF-2 DNA binding with expression profiling of hypoxia-inducible transcripts
This suggests an important role for leucine in mitochondrial adaptation to nutrient changes
Drug-resistant tumor cell lines and oxidative stress are associated with increased cell GSH levels, GCL activity, GCLC mRNA levels and GCLC gene transcription [5763]
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[PubMed: 19226266] 70
