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Human safety data is limited, so its full risk profile is not established

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Multicenter, double-blind, placebo-controlled, randomized phase II trial of gemcitabine/cisplatin plus bevacizumab or placebo in patients with malignant mesothelioma

Rats fed with low-protein diets (which are particularly poor in sulfurated amino acids) will exhibit increased hepatic G-SH and GGT activity, with both returning to baseline values when methionine is added to the low-sulfur diet [19]
