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Vitamin B6 Deficiency and Disease Deficiencies of vitamin B6 are rare and usually are related to an overall deficiency of all the B-complex vitamins

[DOI] [PMC free article] [PubMed] [Google Scholar] 261.Pogribna M., Melnyk S., Pogribny I., Chango A., Yi P., James S.J

The AFBO is highly unstable, and it reacts with cellular nucleophiles and can induce mutations by alkylating DNA, principally at the N 7 position of guanine forming the 8,9-dihydro- 8-(N 7 -guanyl)-9-hydroxy-AFB 1

Doctors noticed that as a side effect of taking this medication for months or years, patients skin tones became significantly lighter

10.1016/j.cgh.2013.06.023