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Many of these factors are cumulative

PEM is a debilitating aspect of all three conditions, leading patients to pace their activities to avoid triggering these symptoms (Stussman et al., 2023

Insert the syringe's needle into the liquid vial and pull up the plunger until all the liquid is in the syringe

developed an electrospun DegraPol tube delivering secretome from a co-culture of adipose-derived stem cells and tenocytes for Achilles tendon repair in rabbits, showing that this cell-free implant significantly reduced adhesion formation (22%), lowered tendon swelling (32% cross-sectional area), and restored near-native load and stiffness, demonstrating its strong potential as a biodegradable, secretome-releasing scaffold to enhance tendon healing and biomechanics (Rieber et al., 2025)