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Moreover, studies in PCOS patients treated with NAC (1.8 g/day for 6 weeks) have shown a decrease in receptor tyrosine kinase c-kit protein levels in follicular fluid, while the expression of growth differentiation factor-9 in mature oocytes increases, suggesting that NAC may enhance oocyte maturation and embryo quality [60]

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February 27, 2026

Yang SY, Taanman JW, Gegg M, Schapira AHV

The detailed mechanism of the gliotoxin-induced mechanism mediated by ROS has been investigated