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Reduce oxidative stress and promote anti-aging Oxidative stress, caused by an imbalance between free radicals and antioxidants, is one of the primary drivers of cellular aging and chronic disease

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However, the CFZ-induced perturbation in mice may be useful to better understand the mechanism of CFZ associated toxicity

(ii) Cu 2+ induces the secretion of acidic SMase from leukocytes which in turn leads to accumulation of erythrocytic ceramide [131] and (iii) treatment of erythrocytes with extracellular SMase resulted in ceramide-associated alterations in membrane-cytoskeleton interactions and membrane organization [125]