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APOLLO-2: a randomized, placebo and active-controlled phase III study investigating oliceridine (TRV130), a G protein-biased ligand at the -opioid receptor, for management of moderate to severe acute pain following abdominoplasty

A: 5-10 days typically
Mice treated with GHK-Cu found the escape hole faster in a maze test, indicating better cognitive performance

The dose and application regimens were as described previously (Duzel et al., 2017
