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Moreover, elevated systemic concentrations of TMAO enhanced thrombosis potential in vivo in animal models (4), and in recent clinical intervention studies, elevation in plasma TMAO induced with dietary choline supplementation altered platelet hyperresponsiveness in subjects (omnivores and vegans/vegetarians alike), as monitored by platelet aggregometry (17)

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Abdominal pain, diarrhoea, nausea and vomiting are some common observe side effects

[7] [9] What are the possible side effects
CNF toxin binds to the tight junctions of colonic epithelial cells which internalize it by endocytosis and promotes cell proliferation by encouraging entry into the cell cycle and the G1/S transition for cell survival by inducing, in particular, the expression of the anti-apoptotic proteins Bcl-2 (B-cell lymphoma 2) and Bcl-xl (B-cell lymphoma-extra-large) [154]