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The 2018 Nobel Prize in Physiology or Medicine: An exemplar of bench to bedside in immunology

Dnes et al., 2008), administration of CXC3L1 to wild-type mice or cx3cl1/ mice showed reduced ischemic lesions in wildtype animals while an increase in lesion sizes was found in knockout littermates, respectively (Cipriani et al., 2017)

These findings reveal that targeting the interaction between PRDX1 and DOK3 to inhibit plasma cell differentiation represents a promising therapeutic approach for RA

doi: 10.1016/j.ebiom.2019.03.018

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