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Meanwhile, mitochondrial damage induces autophagy, and the autophagic system binds to ferritin via NCOA4-mediated selective autophagy, accelerating the disintegration of iron storage pools, releasing a large amount of free divalent iron ions, inducing the Fenton reaction, and ultimately leading to ferroptosis [53]

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Triglyceride (TG) deposition in the mouse liver was insufficient to induce insulin resistance and liver inflammation [34]
