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Although the MASLD definition differs conceptually from traditional NAFLD criteria, multiple validation studies demonstrate high diagnostic concordance between both classification systems (810)

References National Institute of Diabetes and Digestive and Kidney Diseases American College of Surgeons Society of American Gastrointestinal and Endoscopic Surgeons National Health Service Mayo Clinic This article is for general information only and is not a substitute for professional medical advice

With R package MetaboAnalystR, VIP values were extracted from OPLS-DA results containing score and permutation plots

[55], showed that rats, orally receiving radiolabeled LC, metabolized it to -butyrobetaine (up to 31% of the administered dose, present primary in feces) and TMAO (up to 23% of the administered dose, present primary in urine)