l carnitine cause insomnia L-Carnitine and acetyl-L-carnitine roles and neuroprotection in developing brain Mitochondrial-inflammation crosstalk in major depressive

Sleep disturbances affect up to 80% of cirrhosis patients, with insomnia and excessive daytime sleepiness being particularly prevalent

[DOI] [PMC free article] [PubMed] [Google Scholar] 241.Llansola M., Erceg S., Hernndez-Viadel M., Felipo V

A systematic review and meta-analysis of 14 randomized controlled trials demonstrated that L-Carnitine supplementation (1-3 g/day) significantly reduced muscle soreness at 24 hours (weighted mean difference: -6.39, p=0.001) and 48 hours post-exercise (weighted mean difference: -1.53, p=0.03) compared to placebo

The literature pertaining to the impact of LC supplementation on neurological or psychiatric disorders in patients was reviewed up until November 2023

Intralesional therapies, particularly collagenase clostridium histolyticum (CCH), have shown promise