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The average size of the nanospheres from TEM is found to be 18 to 22 nm, which is almost near the average size calculated from the PXRD

Then the macrophages were collected for purification of IL-18+ macrophages

Elevated oxidized low-density lipoprotein (Ox-LDL) levels contribute to the development of major depression by inducing neuroinflammation ( Additionally, a mouse model of AS-related depression was developed using APOE / mice to investigate the underlying pathogenesis

Transl Psychiatry 4 , e469 (2014)

Induction of insulin resistance Obesity, a key risk factor for T2DM, elicits adipose tissue dysfunction and localized chronic inflammation