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Similarly, deleting AMPK1 gene altered the differentiation pathway of M-MDSCs, leading them to adopt a cytotoxic role against tumors through nitric oxide synthase 2, highlighting the central role of AMPK1 in MDSC-mediated immunosuppression

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doi: 10.3390/jof10100686 87 DenningD

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The characteristic symptoms of sepsis are the development of systemic inflammation and multiple organ dysfunction up to the development of septic shock
