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In the BMP pathway, ACVRL1 and ENG are receptors involved in the phosphorylation of SMAD1 and are expressed in the mature lung vasculature

For GSEA, genes were ranked by the t-statistic of the Lm coefficient in the linear mixed-effects model and then analyzed for the enrichment of canonical pathways and Gene Ontology term gene sets obtained from MSigDB v2.5

Amiri M, Hollenbeck PJ (2008) Mitochondrial biogenesis in the axons of vertebrate peripheral neurons

Rather, it is explained by the larger presynaptic active zones and PSDs in human that may allow higher release probability as well as more neurotransmitter release and binding (Benavides-Piccione et al

Compare BPC-157 by mechanism, evidence strength, expected timeline, side-effect profile, and whether its primary use case matches your goal
