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This suggests that long-term maintenance on an LD rich in carbohydrates may confound some of the microbiome differences commonly reported between mice on HFDs and those on lean control diets which contain fewer carbohydrates

In studies using obese murine models, AOD9604 administration was associated with increased lipolysis that coincided with elevated 3-AR mRNA expression, supporting the hypothesis that the peptide sensitizes fat cells to lipolytic signaling rather than simply forcing fat breakdown through a separate pathway

No, their efficacy is comparable