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In this electron flow, O 2 can be reduced through various pathways, including the generation of O 2 , the formation 1 O 2 , or the production of H 2 O 2

We analyze a number of cellular and molecular markers, typical of ocular hypertension and, in general, of the cell stress response

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TSA treatment causes an increase in global histone acetylation in all marks analyzed over time in ACLY KO cells, and this effect is comparable in DKO cells (Figure 4C)