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MCheM mapping identified optimal cofactor pairs: Vitamin C, ALA, and milk thistle silymarin all of which stabilize the redox cycle and regenerate oxidized glutathione (GSSG GSH)

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However, the efficacy of glutamine supplementation is frequently questioned due to confusing and controversial results [150,168,169]

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Abstract The tripeptide glutathione (GSH) is the most abundant intracellular nonprotein thiol, and it is involved in many cellular functions including redox-homeostatic buffering

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