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Furthermore, in the RAS WT subgroup, the ORR (PRc) was 50.0%, the DCR was 83.3%, the median PFS was 6.3 months, and the median OS was not reached (Saeed et al., 2022)
Notably, lung cancer stem cells maintain a distinct metabolic profile by upregulating BCAA transporters, which may contribute to therapy resistance [32,33,34]
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IGFBP2 enhances adipogenic differentiation potentials of mesenchymal stem cells from Whartons jelly of the umbilical cord via JNK and Akt signaling pathways
Insulinlike growth factors and cancer: from basic biology to therapeutics
