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[PubMed: 12364482] 321

No More Is Always Better Mentality: While B12 is generally safe, taking excessive amounts when not needed simply means your body will excrete the excess, making it a waste of money and potentially masking underlying issues if youre self-treating

NNMT is a metabolic enzyme widely distributed in the cytoplasm of human cells

The treatment plan is a loading phase of injections every other day for around two weeks, then maintenance every two to three months for life when the cause is not dietary, or twice a year when it is

However, low levels are rare in most healthy adults because the human liver stores vitamin B12 over time