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Vitamin B12 overdose Symptoms: Headache Nausea and vomiting Bloating Diarrhea Fatigue and weakness Tingling in hands and feet Dizziness Itchy, burning skin Acne High blood pressure There are few studies for vitamin B12 overdose, but some medical experts suggest potential harm from B12 overload: May increase the risk for heart attack and stroke Too much vitamin B12 and folate during pregnancy may increase the risk of autism in offspring Could increase the risk for cancer May shorten lifespan High C-reactive protein (CRP) combined with vitamin B12 overload decreases the survival of cancer patients Its unlikely that high vitamin B12 can occur without the overuse of high-efficiency oral or injectable B12

doi: 10.1056/NEJM198806303182604

Studies in animal models have indicated that Dihexa administration can affect body weight, glucose metabolism, and insulin sensitivity

Neurological symptoms, including tingling in the hands and feet, memory loss, and mood changes, may occur as B12 is crucial for nerve health

A number of researchers have called for the replacement of cyanocobalamin in supplements with other, safer forms of vitamin B12 listed above
