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Description
Originally developed as anti-epileptic medications, gabapentinoids have become widely used for the treatment of neuropathic pain and a range of other conditions

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Under normal conditions, when ROS are present at low levels, they serve as secondary messengers for neurotransmission and differentiation

In patients with mild cognitive impairment (often a precursor to Alzheimers disease), prolonged melatonin supplementation reportedly slowed the progression of cognitive decline and improved sleep and mood, though larger trials are needed