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2020;159(6):2092-2100.e5

Leucine-rich repeat and immunoglobulin-like domain-containing protein 1 (LINGO-1), which was discovered by Biogen, 16 suppresses oligodendrocyte differentiation, axonal regeneration, and neuronal survival
G.Darley-UsmarV

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This inhibition causes AICAR to accumulate intracellularly
