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The theoretical risk of uncontrolled angiogenesis has been raised in mechanistic discussions and has not been adequately ruled out in humans (but dont take this as any sort of positive evidence that BPC-157 causes cancer0

In addition to Glr1, the cytosol and matrix contain various alternative GSSGreducing enzymes including thioredoxins, peroxiredoxins and glutaredoxins (Pedrajas et al , 1999
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R.CrouchB.KwiatekR.BurnetR.MernoneA.ChryssidisS.et al (2011)

The induction of targets, such as GCL, requires the activation of upstream transcriptional co-activators