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The 12mg cohort achieved the highest mean body weight reduction at -24.2% exceeding all published results for semaglutide (approximately -16% in the STEP trials) and tirzepatide (approximately -22.5% in SURMOUNT-1) at their respective maximum doses

B12 is included to aid in the production of red blood cells, support nerve health of nerves and support metabolic functions

However, the conversion introduced greater specificity requirements
