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Figure 3 3.3 Metabolic pathways: microbial metabolites and pain modulation The gut microbiota is a major metabolic organ that produces many metabolites with diverse physiological effects (82)

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Because of their already highly sensitized bodies and a low threshold of stimulatory excitation response, any product including methylated folate or methylated B12 can further increase an excitation response and trigger an adrenal crash

The effect of seasonal temperatures on the physiology of the overwintered honey bee

Accordingly, antioxidant interventions are unlikely to be universally effective, and their benefit may depend on selective modulation of pathological redox imbalance