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[DOI] [PMC free article] [PubMed] [Google Scholar] Higgins 2009 Higgins JPT, Thompson SG, Spiegelhalter DJ

Her nurse applied a cool compress, advised skipping strenuous exercise for one day, and suggested a quick telehealth check if anything worried her

[2] Oral B12 supplementation generally takes longer to produce effects , with patients often noticing energy improvements within two to four weeks

Other side effects reported ranged from lipohypertrophy at injection site, papilloedema (related to cranial hypertension), and facial nerve paralysis [276, 285], however symptoms did not prevail after treatment pause and restarting with lower doses [268]