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The animal study results are promising enough that it has become one of the most widely self-administered research peptides, but the absence of human trial data means all dosing is extrapolated from animal models adjusted for body weight.

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JAK2 activation in BPC-157-treated tendon fibroblasts occurs in a time-dependent manner following growth hormone stimulation, indicating the peptide primes cells for enhanced growth factor responsiveness rather than directly activating the pathway in the absence of the endogenous ligand

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