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Saturated fatty acids are known to increase the production of lipotoxic products such as ceramide and diacylglycerol, which disrupt islet beta-cell function, vascular reactivity and mitochondrial metabolism, and also play a key role in the induction of muscle IR (199201)

Food Sci Technol Int (2013) 19:1123
These phenomena were attributed to the different transport characteristics of OCTN2 and ATB 0,+

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