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Description
Specifically, we analyzed affected brain areas (04), cerebral (NTP-7, Level 3), cerebellar cortex (NTP-7, Level 6), and the hippocampus, thalamus, and hypothalamus (NTP-7, Level 3) as follows (score 0 indicates no histopathologic change): score 1: small, patchy, complete or incomplete infarcts (10% of area affected)
Fluid markers of traumatic brain injury
Subsequent work by Sun and colleagues in the APP/PS1 mouse model identified downstream PI3K/AKT pathway activation as a major component of the mechanism, with the PI3K inhibitor wortmannin reversing Dihexas anti-inflammatory and anti-apoptotic effects [5]
Rats were recorded and afterwards assessed (slow-down video) for forelimb function impairment
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