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10.1161/ATVBAHA.119.313115 42 De PasqualeL.D'AmicoA.VerardoM.PetriniS.BertiniE.De BenedettiF

People who are regularly exposed to toxins (alcohol, pollution, certain medications, or chemicals) might notice they feel more sluggish or foggy when they stop treatments

Selinay Demirel, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

M1 macrophage metabolism is characterized by enhanced aerobic glycolysis, conversion of glucose to lactate, increased flux through the Pentose Phosphate Pathway (PPP), fatty acid synthesis, and a truncated tricarboxylic acid (TCA) cycle, leading to the accumulation of succinate and citrate