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Iron accumulation within the cell can enhance the fenton reaction, generating more hydroxyl radicals and promoting lipid peroxidation, thereby facilitating ferroptosis

Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms

Bound antibodies were visualized with horseradish peroxidase (HRP)-conjugated anti-rabbit IgG or anti-mouse IgG (Jackson ImmunoResearch Laboratories, Baltimore Pike West Grove, PA, USA) and immunoreactivity assessed by chemiluminescence reaction, using the ECL Western detection system (Millipore, Darmstadt, Germania)

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Nevertheless, two GLXI-like genes, GlxI-like;4 and GlxI-like;7 , were transcriptionally induced