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Another potent oral PARP1/2 inhibitor, niraparib (MK4827) binds to the active site of PARP enzymes, and studies indicate that Niraparib can restore NAD + levels and improve mitochondrial function 165,166

[DOI] [PubMed] [Google Scholar] 59.Singh S., Nwabor O.F., Sukri D.M., Wunnoo S., Dumjun K., Lethongkam S., Kusolphat P., Hemtanon N., Klinprathum K., Sunghan J., et al

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