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[DOI] [PubMed] [Google Scholar] 8.Lahiri S.W

First, ADO is produced in the BM niches where MM cells grow

While spatial memory retrieval remained intact, longer diabetes duration and frequent severe episodes of hypoglycaemia in the 2 weeks preceding vMWMT analysis were linked to poorer visuospatial task performance

However, we know now that other forms of cell death, such as necroptosis, ferroptosis, and inflammasome mediated cell death/pyroptosis lead to oligodendrocyte death in the cuprizone model and occur at different time points after intoxication

It activates multiple overlapping pathways simultaneously, which is part of why its effects appear so broad