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We acknowledge a possibility that the elusive high-affinity kinetically stabilising site could be located at the flexible interface between the regulatory domains and hence difficult to be resolved in cryo-EM studies

[DOI] [PubMed] [Google Scholar] Larsen G.L., Bakke J.E

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This research has been funded by Deputy for Research and Innovation, Ministry of Education through Initiative of Institutional Funding at University of Hail Saudi Arabia through project number IFP-22017

The balance between spine formation and elimination determines the change in spine density: a surplus of spine formation over elimination along a dendritic segment increases spine density thereon, and vice versa