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In particular, lack of early response appears to be strongly indicative of subsequent nonresponse [2], failure to achieve remission [3], and higher rates of treatment discontinuation [4]

This effect may be due to the upregulation of antioxidant stress genes, including superoxide dismutase 1 (SOD1) and dual oxidase 1 [8]

Previous studies demonstrated that LRRK2 and PINK1 mutations promote dopaminergic neuronal toxicity

B sung Glutathione c tc ng tch cc n sinh kh dng ca vitamin D, gip cho c th d dng s dng vitamin D hn

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