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P., et al., Deficiency of Inducible and Endothelial Nitric Oxide Synthase Results in Diminished Bone Formation and Delayed Union and Nonunion Development, Bone 83 (2016): 111118

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Once DNA or RNA non-enveloped virus or intracellular bacteria coated with antibodies enter into cells, TRIM21 is bound and stimulated, which works together with ubiquitin enzymes to target the antibody-coated microbes for destruction via the cellular waste disposal system

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