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180,181,183 GLP-1 also activates the phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) pathway, which is crucial for maintaining the survival and function of pancreatic -cells
Popovici J, Pierce-Friedrich L, Kim S, Bin S, Run V, Lek D, Hee KHD, Lee Soon-UL, Cannon MV, Serre D, Menard D
The GIP component enhances insulin sensitivity in fat tissue and may promote beneficial fat metabolism, building on the same principle that makes tirzepatide dosing effective
